Bio-Modeling Systems: The Mechanisms-Based Mecidicine Company
  • 2018: POSITION PAPER : Paris November 5, 2018: Why Human Augmented Intelligence, the other AI, can "cure" the "Pharma chronic"too high failure rate" syndrome

  • 2018: ANNOUNCEMENT: BMSystems invited to present its CADI Discovery platform and achievements at 4 events in Europe,BioFit,-BioWin-Day,COST EC cluster conference, DGA BtoB  

  • 2018: PRESSE-RELEASE: L’Association Française du Syndrome de Fatigue Chronique (AFSC) change les règles du jeu et s’associe à Bio-Modeling Systems pour développer et valider un modèle explicatif et thérapeutique de l'EM/SFC (CFS/ME).

  • 2018: PRESS-RELEASE: Paris October 10, 2108: Bio-Modeling Systems, with its operational CADI™ Discovery platform, is the Integrative Biology partner of GEMMA (autism & microbiota) project selected for €14.2M H2020 funding by the European Commission to identify potential targets for the personalized treatment and prevention of Autism Spectrum Disorderss

  • 2018: PRESS-RELEASE: Paris 10 Octobre 2108: Bio-Modeling Systems, avec sa plateforme opérationnelle CADI™ Discovery est le partenaire « Biologie Intégrative » du  programme GEMMA (autisme & microbiote) sélectionné par la Commission européenne pour un financement H2020 de 14,2 millions d'euros afin d'identifier des cibles potentielles pour le traitement personnalisé et la prévention des troubles du spectre autistique

  • 2018: ANNOUNCEMENT: Paris September 4, 2018: How CADI Discovery, invented in 2004,  successfully addressed the "Garbage in Garbage out" Law of every Data Processing explained in Current Opinion in Pharmacology:  How scientific literature analysis yields innovative therapeutic hypothesis through integrative iterations.
     
  • 2018: PRESS-RELEASE: Paris  July17, 2018: World's first: The French Chronic Fatigue Syndrome Association decides to clinically evaluate the ME/CFS pathogenesis model produced by Bio-Modeling System.s

  • 2018: ANNOUNCEMENT: Paris June 19-20, 2018: BMSystems invited to the Microbiotes conference organized by Adebiotech to present its microbiota vision and CADI Discovery programs. 

  • 2018: ANNOUNCEMENT: Paris June 14, 2018: BMSystems invited to the Connected Health Conference organized by ANRT to present its Real life data strategy with its "patients & HCP digital pathways" partner Bolero.

  • 2018: ANNOUNCEMENT: Paris March 13-14, 2018: BMSystems invited to the Epigentic conference organised by Adebiotech to present its CADI Discovery program EPIGEN-DIAB with the Centrer of excelllence in Epigenetic in India.
Bio-Modeling Systems: The Mechanisms-Based Mecidicine Companys

CADI™ (Computer Assited Deductive Integretion) Discovery - Value Generation


CADI™ state of the Art first collaborative research programs

  • A collaborative research between the SEPIA laboratory from the François Jacob Institute of biology par of CEA and Bio-Modeling Systems in the field of prion diseases led to a world’s first in vivo validation of the mechanisms of Creutzfeldt-Jakob disease pathogenesis & progression. Two Awards (2009 and 2010).
  • A collaborative research between the SEPIA laboratory from the François Jacob Institute of biology par of CEA and Bio-Modeling Systems in the field of prion diseases led to the filing of the co-owned patent WO201029131 describing a novel therapeutic strategy to treat psychiatric and neurological disorders. This patent is licensed exclusively on a worldwide basis to Theranexus, a CEA spin-off company.
  • A Colllaborative research in the field of biodefence and Multi-resistant bacterias threats has led to  Pherecydes-Pharma (2006): BMSystems’ spin-off, ( novel M.R. anti-bacterial nano-agents biotherapies), two indications:  Skin infections in Phase I/II. & osteo-articular infections.

Technology Developments (know-how, patents)

  • CADI™ Computer-Assisted Deductive Integration, proprietary methodologies and tools.
  • CADI™ Search (data acquisition & mining).
  • CADI™ Architect (data organization & structuring).
  • CADI™ Fiber-N (integrative engine).
  • CADI™ View (model representation & visualization).
  • TAPE Patent: WO/2008/093010- December 2006.
  • AB-ACCUS patent: WO/2008/093009 - December 2006.
  • RIPh patent: PCT/FR2010/050796 – May 2009.
  • CNS copatent: WO/2010/029131 - Use of anti-connexin agents for modulating the therapeutic effect of psychotropic drugs. September, 2008

Valorisation of our collaborative research:

  • Spin-off (equity, etc,...).

  • Out-Licensing (royalties, etc,...).

  • Consortiums / J.V. (fees, royalties).

Contract Research (fees and possible royalties)

For more details download our Corporate Presentation

Bio-Modeling Systems: a leading Integrative Heuristic Systems Biology / Predictive Integrative Biology Mechanisms-Based Medicine company that delivers